OR6M1

Protein-coding gene in the species Homo sapiens
OR6M1
Identifiers
AliasesOR6M1, OR11-271, olfactory receptor family 6 subfamily M member 1
External IDsHomoloGene: 107073; GeneCards: OR6M1; OMA:OR6M1 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR6M1
Genomic location for OR6M1
Band11q24.1Start123,805,408 bp[1]
End123,806,349 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • mucosa of transverse colon

  • body of pancreas

  • right lobe of liver

  • rectum

  • superior frontal gyrus

  • placenta
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • signal transducer activity
  • olfactory receptor activity
  • G protein-coupled receptor activity
Cellular component
  • plasma membrane
  • membrane
  • integral component of membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • detection of chemical stimulus involved in sensory perception of smell
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

390261

n/a

Ensembl

ENSG00000196099

n/a

UniProt

Q8NGM8

n/a

RefSeq (mRNA)

NM_001005325

n/a

RefSeq (protein)

NP_001005325

n/a

Location (UCSC)Chr 11: 123.81 – 123.81 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 6M1 is a protein that in humans is encoded by the OR6M1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196099 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR6M1 olfactory receptor, family 6, subfamily M, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
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Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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